Dexketoprofen belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, dexketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain.
Adult: 12.5 mg every 4-6 hr or 25 mg every 8 hr. Max: 75 mg/day.
Elderly: Initial total daily dose should not exceed 50 mg/day. May increase to the doses recommended for general population only if well tolerated.
Mild renal impairment: Reduce initial dose to 50 mg/day. Not to be used in moderate to severe renal impairment.
Mild to moderate impairment: Reduce initial dose to 50 mg/day. Not to be used in severe hepatic impairment.