A benzodiazepine class of drug. Reduces neuronal excitability through influx of a great quantity of chloride ion by potentiating the efficacy of GABA. Indications: Anxiety, Depression, Panic attack, Insomnia etc. Dosage & Administration: The usual dose is 0.25-0.5 mg three times daily. Extended release tablet: 1-3 mg once daily. Use in pregnancy & lactation: US FDA Pregnancy category D.
Alprax Tablet 0.25 mg
Must be individualized and carefully titrated in order to avoid excessive sedation or mental and motor impairment.
For Adults: Initially 0.25 mg given 2 or 3 times daily. If required, increases may be made in 0.25 mg increments according to the severity of symptoms and patient response.
It is recommended that the evening dose should be increased before the daytime doses. Very severe manifestations of anxiety may require larger initial daily doses. The optimal dosage is one that permits symptomatic control of excessive anxiety without impairment of mental and motor function. Exceptionally, it may be necessary to increase dosage to a maximum of 3 mg daily, given in divided doses.
For Elderly and Debilitated Patients: The initial dosage is 0.125 mg 2 or 3 times daily. If necessary, this dosage may be increased gradually depending on patient tolerance and response.