Amdocal Plus® is a fixed dose combination of Amlodipine Besilate and Atenolol. Amlodipine Besilate is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Atenolol is (2-Hydroxy-3-isopropyl- aminopropoxy) phenylacetamide, a selective b1 blocker. Amdocal Plus used in the treatment of Hypertension not controlled by monotherapy, Angina pectoris & hypertension co-existing diseases, Post M.I patients. Refractory angina pectoris where nitrate therapy has failed.
Amdocal Plus Tablet
The recommended dosage is one tablet of Amdocal Plus® 50 (Amlodipine 5mg and Atenolol 50mg) or Amdocal Plus® 25 (Amlodipine 5mg and Atenolol 25 mg). Depending upon the therapeutic response, titration of the dosage is recommended. In elderly patients, it is advisable to initiate the therapy with 1/2 tablet of fixed dose combination of Amlodipine & Atenolol i.e. 2.5 mg Amlodipine & 25 mg Atenolol.