Amodis Tablet

৳ 1.01

Metronidazole
(in tablet form)

Dosage:
Oral-
Amoebiasis:

Adult: 800 mg tid for 5 days (intestinal infection); 5-10 days (extra-intestinal infection). Max: 2.4 g/day.
Child: 1-3 yr 100-200 mg tid; >3-7 yr 100-200 mg 4 times daily; >7-10 yr 200-400 mg tid. Doses are given for 5-10 days.

Prophylaxis of postoperative anaerobic bacterial infections:

Adult: 400 mg 8 hrly 24 hr prior to surgery followed by post-op IV or rectal admin until oral therapy is possible.
Child:

Giardiasis:

Adult: 2 g once daily for 3 days, 400 mg tid for 5 days or 500 mg bid for 7-10 days.
Child: 1-3 yr 500 mg once daily; >3-7 yr 600-800 mg once daily; >7-10 yr 1 g once daily. Doses are given for 3 days.

Anaerobic bacterial infections:

Adult: Initially, 800 mg followed by 400 mg 8 hrly. Alternatively, 7.5 mg/kg 6-8 hrly. Max: 4 g/day. Duration of treatment is usually for 7 days depending on the severity of infection.
Child:

Bacterial vaginosis:

Adult: 2 g as a single dose or 400 mg bid for 5-7 days.

Trichomoniasis:

Adult: 2 g as a single dose, 200 mg tid for 7 days or 400 mg bid for 5-7 days. Sexual partners should also be treated. Repeat treatment 4-6 wk between courses as necessary.
Child: 1-10 yr 40 mg/kg as a single dose or 15-30 mg/kg daily in 2-3 divided doses for 7 days. Max: 2 g/dose.

Leg ulcers and pressure sores:

Adult: 400 mg tid for 7 days.

Eradication of H. pylori associated with peptic ulcer disease:

Adult: 400 mg bid in combination with another antibacterial and a PPI or 400 mg tid, if given with omeprazole and amoxicillin. Initial treatment is given for 1 wk.

Acute necrotising ulcerative gingivitis:

Adult: 200 mg tid for 3 days.
Child: 1-3 yr 50 mg tid; >3-7 yr 100 mg bid; >7-10 yr 100 mg tid. Doses are given for 3 days.

Acute dental infections:

Adult: 200 mg tid for 3-7 days.

Intravenous-
Prophylaxis of postoperative anaerobic bacterial infections:

Adult: 500 mg shortly before operation and repeated 8 hrly. Alternatively, 15 mg/kg infused over 30-60 min and completed approx 1 hr before surgery, followed by 7.5 mg/kg infused over 30-60 min at 6 and 12 hr after the initial dose.

Anaerobic bacterial infections:

Adult: 500 mg infused as 100 mL of a 5 mg/mL soln at 5 mL/min 8 hrly. Alternatively, 15 mg/kg infused over 1 hr, followed by 7.5 mg/kg infused over 1 hr 6 hrly. Max: 4 g/day. Substitute oral therapy as soon as possible.
Child: 7.5 mg/kg 8 hrly.

Manufacturer: Square Pharmaceuticals Ltd.