Anadol Injection
৳ 20.07
Oral
Moderate to severe pain:
Adult: 50-100 mg 4-6 hrly. Extended-release tab: 50-100 mg once or twice daily. Max: 400 mg/day.
Elderly: >75 yr Increase dosing interval.
Parenteral
Postoperative pain:
Adult: Initially, 100 mg followed by 50 mg every 10-20 min if necessary, to a total of 250 mg in the 1st hr including initial dose. Thereafter, 50-100 mg 4-6 hrly up to a total daily dose of 600 mg.
Elderly: >75 yr Increase dosing interval.
Parenteral
Moderate to severe pain:
Adult: IM/IV: 50-100 mg 4-6 hrly over 2-3 min.
Elderly: >75 yr Increase dosing interval.
Tramadol is a centrally acting synthetic analgesic compound. It inhibits the re uptake of neurotransmitters- serotonin and noradrenaline. Thus it modifies the transmission of pain impulses by activating both descending serotonergic pathways and noradrenergic pathways involved in analgesia. The analgesic effects of Tramadol are mediated via stimulation of mu-opioid receptors and indirect modulation of central monoaminergic inhibitory pathways.
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