Adapalene is a retinoid-like compound. Biochemical and pharmacological profile studies have demonstrated that adapalene is a potent modulator of cellular differentiation, keratinisation and inflammatory processes all of which represent important features in the pathology of acne vulgaris. Adapalene binds to specific retinoic acid nuclear receptors that normalises the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.
Apalene 0.1% Cream
Cream: It should be applied to the affected areas of skin, once daily at night-time
Gel: It should be applied to the entire face and any other affected areas of the skin, once daily in the evening.
A thin film of gel or cream should be applied to the skin areas where lesions present, using enough to cover the entire affected areas lightly