Bevixa 100 IV Infusion

Bevacizumab should not be administered as an IV push or bolus
Bevacizumab should not be initiated for 28 days following major surgery and until surgical wound is fully healed
• Metastatic colorectal cancer
5 mg/kg IV every 2 weeks with bolus-IFL
10 mg/kg IV every 2 weeks with FOLFOX4
5 mg/kg IV every 2 weeks or 7.5 mg/kg IV every 3 weeks with fluoropyrimidine-irinotecan or fluoropyrimidine-oxaliplatin based chemotherapy after progression on a first-line Bevacizumab containing regimen
• Non-squamous non-small cell lung cancer
15 mg/kg IV every 3 weeks with carboplatin/paclitaxel
• Glioblastoma
10 mg/kg IV every 2 weeks
• Metastatic renal cell carcinoma (mRCC)
10 mg/kg IV every 2 weeks with interferon alfa
• Persistent, recurrent, or metastatic carcinoma of the cervix
15 mg/kg IV every 3 weeks with paclitaxel/cisplatin or paclitaxel/topotecan
• Platinum-resistant recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer
10 mg/kg IV every 2 weeks with paclitaxel, pegylated liposomal doxorubicin or weekly topotecan 15 mg/kg IV every 3 weeks with topotecan given every 3 weeks

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