Cinnarizine acts as an antihistamine, labyrinthine sedative and a peripheral antivasoconstrictor. Inarzin is a selective calcium antagonist, inhibiting the influx of Ca2+ intracellularly. It prevents the Ca2+ dependent contraction of arterial smooth muscle by inhibiting Ca2+ influx through smooth muscle calcium channels and thereby, improves vestibular symptoms and prevents peripheral arterial disease
Cinaryl Tablet 15 mg
Peripheral vascular disease:
Adult: 75 mg bid or tid.
Adult: 75 mg once daily.
Adult: 30 mg 2 hr before travel then 15 mg 8 hrly during the journey if necessary.
Child: 5-12 yr 15 mg 2 hr before travel then 7.5 mg 8 hrly during the journey as necessary.
Vertigo and vestibular disorders:
Adult: 30 mg tid or 75 mg 1-2 times daily.
Child: 5-12 yr 15 mg tid.