Clindamycin Phosphate is a water soluble ester that derived from the parent antibiotic Lincomycin. Clindamycin inhibits bacterial protein synthesis by binding preferentially to the 50s ribosomal subunit and affects the process of peptide chain initiation. In vitro Clindamycin is active against most strains of the following organisms that have been reported to be associated with bacterial vaginosis:
– Bacteroides spp.
– Gardnerella vaginalis
– mMobiluncus spp.
– Mycoplasma hominis
– Peptostreptococcus spp.