Dexamethasone is one of the most potent corticosteroids; it is 5 -14 times more potent than prednisolone and 25 – 75 times more potent than cortisone and hydrocortisone. Of paramount importance with regard to local therapy is the fact that dexamethasone is over 2000 times more soluble than hydrocortisone or prednisolone. The addition of chloramphenicol, a broad-spectrum antibiotic, has made this combination yield excellent results in inflammation of the anterior uvea.
Dexaguard Eye Drop
1 or 2 drops is instilled into the affected eyes every 3 or 4 hours, or more frequently if deemed advisable by the prescribing physician. Administration should be continued day and night for the first 48 hours, after which the interval between applications may be increased. Treatment should be continued for at least 48 hours after the eye appears normal.