Nitrazepam is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.
Epam Tablet 5 mg
Short-term management of insomnia:
Adult: 5 mg at night; increase to 10 mg if necessary.
Elderly: and debilitated patients: ≤normal adult dose.
Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.
May be taken with or without food