Ephedrine stimulates both α- and β-receptors, thereby causing bronchodilation, peripheral vasoconstriction and CNS stimulation. It also has stimulant action on the resp centre.
Epidron Injection 25 mg/5 ml
Adult: 15-60 mg tid.
Child: 1-5 yr: 15 mg tid; 6-12 yr: 30 mg tid; >12 yr: Same as adult dose.
Elderly: Initial: 50% of adult dose.
Reversal of spinal or epidural anaesthesia-induced hypotension:
Adult: 3-6 mg by slow IV inj every 3-4 min as required. Max total dose: 30 mg.
Child: 0.5 mg/kg or 16.7 mg/m2 4-6 hrly by SC or IM inj or alternatively, 0.75 mg/kg or 25 mg/m2 4 times daily by SC or IV inj.
Elderly: Same as adult dose.
Adult: 12.5-25 mg by SC, IM or IV inj, further dosage may be given according to patient’s response.
Adult/Elderly: As 1% soln: Instill 1-2 drops into each nostril up to 4 times daily as needed.
Child: >12 yr: Same as adult dose.