Drotaverine has antispasmodic effect mediated via inhibition of phosphodiesterase-IV, specific for smooth muscle. It has a rapid and direct action on the smooth muscle. It acts to correct cyclic AMP and Ca imbalance at the spastic site, thereby relieving smooth muscle spasm and pain.

Espa Injection
৳ 70.23
Oral-
Adults: 1 to 2 tablets, 3 times daily
Children (over 6 years): 1/2 to 1 tablet, 1-2 times daily.
Children (1-6 years): 1/4 to 1/2 tablet, 1-2 times daily.
Injection-
Adults: 1 to 2 ampoules, intramuscularly or subcutaneously, 1-3 times daily.
For the management of acute stone colics: 1 or 2 ampoules by slow intravenous injection.