Femzole® tablet is the preparation of Letrozole which is a nonsteroidal aromatase inhibitor. Femzole® (Letrozole) works by inhibiting aromatase enzyme. Therefore, Androgen conversion to Estrogen (through aromatization process) is Inhibited. This results in decreased amount of Estrogen.
Adult and Elderly Patients
The recommended dose of Femzole® tablet is 2.5 mg once daily, without regard to meals. Treatment with Letrozole should continue until tumor progression is evident.
No dose adjustment is required for elderly patients. Patients treated with Letrozole do not require glucocorticoid or mineralocorticoid replacement therapy.
Children: Not recommended for use in children.
Patients with hepatic and/or renal impairment
No dosage adjustment is required for patients with mild to moderate hepatic impairment (child-Pugh grade A and B) or renal impairment (creatinine clearance > 10 ml/ min).