Ofloxacin is a synthetic 4-fluoroquinolone antibacterial agent with bactericidal activity against a wide range of Gram-negative and Gram-positive organisms. Ofloxacin is thought to exert bactericidal effect by inhibiting DNA gyrase, an essential enzyme that is a critical catalyst in the duplication, transcription and repair of bacterial DNA.
Flocet Tablet 200 mg
৳ 10.60
Intravenous (Adult)-
Skin and soft tissue infections: 400 mg bid infused over at least 1 hr.
Complicated urinary tract infections: 200 mg daily by infusion over at least 30 min. Max: 400 mg bid infused over at least 1 hr.
Lower respiratory tract infections, Septicaemia: 200 mg bid by infusion over at least 30 min. Max: 400 mg bid infused over at least 1 hr.
Ophthalmic-
Conjunctivitis, Keratoconjunctivitis
Adult: Instill 1-2 drops in the affected eye(s) every 2-4 hr for the 1st 2 days, then 4 times daily. Max duration: 10 days.
Child: >1 yr Same as adult dose.
Oral (Adult)-
Non-gonococcal cervicitis/urethritis due to Chlamydia trachomatis, Uncomplicated genital infections due to Chlamydia trachomatis: 400 mg daily in single or divided doses for 7 days.
Lower respiratory tract infections: 400 mg daily preferably in the morning, increased to 400 mg bid as required.
Pelvic inflammatory disease: 400 mg bid for 14 days.
Uncomplicated gonorrhoea: 400 mg as a single dose.
Urinary tract infections: 200-400 mg daily preferably in the morning. If necessary, increase in upper UTI to 400 mg bid.
Skin and soft tissue infections: 400 mg bid.
Prostatitis: Acute or chronic: 200 mg bid for 28 days.
Otic/Aural-
Acute otitis media:
Child: with tympanostomy tubes: 1-12 yr Instill 5 drops into the canal of the affected ear(s) bid for 10 days. Lie with the affected ear upwards for 5 min; pump the targus of the ear 4 times by pushing inward to facilitate penetration of the drops into the ear.
Otitis externa:
Adult: Instill 10 drops into the canal of the affected ear(s) once daily for 7 days. Lie with the affected ear upwards for 5 min to facilitate penetration into the ear.
Child: 6 mth to 13 yr Instill 5 drops into the canal of the affected ear(s) once daily for 7 days; >13 yr Same as adult dose.
Otitis media:
Adult: Chronic suppurative with perforated tympanic membranes: Instill 10 drops into the canal of the affected ear(s) bid for 14 days. Lie with the affected ear upwards for 5 min; pump the targus of the ear 4 times by pushing inward to facilitate penetration of the drops into the ear.
Child: ≥12 yr Same as adult dose.