LebacTM(Cephradine) is used in the treatment of infections caused by sensitive organisms.
Upper respiratory tract infections: Pharyngitis, sinusitis, otitis media, tonsilitis,
laryngotracheo-bronchitis; Lower respiratory tract infections: Acute and chronic bronchitis,
lobar and bronchopneumonia. Urinary tract infections: C Cystitis, urethritis, pyelonephritis; Skin
and soft tissue infections: Abscess, cellulitis, furunculosis, impetigo; Gastrointestinal tract
infections: Bacillary dysentery, enteritis, peritonitis. Bone and joint infection; Surgical
prophylaxis: It is also used in perioperative prophylactic administration (pre-operatively,
intra-operatively and post-operatively). In cesarean section, intra-operative (after clamping
the umbilical cord) and post-operative use may reduce the incidence of certain postoperative
(in Capsule form)
Oral: The usual dose is 1-2 gm daily in 2 to 4 divided doses. In severe and prolonged infection, the dose can be increased up to 4 gm daily which should be taken in equally divided doses.
Injection: The usual dose is 2-4 gm daily which should be given intramuscularly or intravenously in 3-4 divided doses.
Special dose in the following infections:
Skin and skin structures and respiratory tract infection: Usual dose is 250 mg every 6 hours or 500 mg every 12 hours.
Lobar pneumonia: 500 mg every 6 hours or 1 gm every 12 hours.
Urinary tract infection: Usual dose is 500 mg every 12 hours.
Gastro-intestinal tract infection: 500 mg three to four times daily.
Oral: The usual total dose is 25 to 50 mg/kg/day given in 2 to 4 equally divided doses.
Manufacturer: Square Pharmaceuticals Ltd.