Lozana is a weak impeded androgen with associated anabolic properties. It inhibits gonadotropin-releasing hormone and gonadotropin secretion. This suppresses menstruation, inhibits ovulation, and causes regressive change in the vaginal smear and atrophic change in the endometrium. Danazol has no estrogenic or progestational properties.
Lozana 100 Capsule
Preoperative thinning of the endometrium:
Adult: 400-800 mg daily, in up to 4 divided doses for 3-6 week.
Benign breast disorders:
Adult: Initially, 100-400 mg daily in 2 divided doses adjusted according to response and continued for 3-6 month.
Adult: Initially, 200 mg bid-tid reduced thereafter according to patient’s response.
Adult: 200-800 mg daily in 2 divided doses adjusted according to response, for 3-6 month or if necessary, up to 9 month.
Adult: 200 mg once daily. Review treatment 3 month later.
Adult: Male adolescents: Initially, 200 mg daily, may increase to 400 mg daily after 2 month if no response occurs; adult men: Initial: 400 mg daily in up to 4 divided doses. Usual treatment duration: 6 month.
Child: Male adolescents: Initially, 200 mg daily increased to 400 mg after 2 month if no response occurs. Treatment usually up to 6 months.