Homatropine, a tertiary amine antimuscarinic, produces dilation and loss of accommodation by blocking the response of iris sphincter muscle and the accommodative ciliary muscle to cholinergic stimulation.
Matropin Eye Drop 2%
Mydriasis and cycloplegia for refraction:
Adult: Instill 1 or 2 drops of 2% solution, or 1 drop of 5% solution immediately before the procedure, repeat at 5-10 minute intervals if necessary.
Child: Instill 1 drop of 2% soln immediately before the procedure, repeat at 10-min intervals if necessary.
Adult: Instill 1-2 drops of 2% or 5% solution bid-tid up to every 3-4 hr as needed.
Child: 3 mth- 2 yr: instill 1 drop of 0.5% soln once daily or on alternate days. >2 yr: instill 1 drop of 1% or 2% soln bid.