Ranitidine competitively blocks histamine at H2-receptors of the gastric parietal cells which inhibits gastric acid secretion. It does not affect pepsin secretion, pentagastrin-stimulated intrinsic factor secretion or serum gastrin.
Neotack Tablet 150mg
(in Tablet form)
Prophylaxis of acid aspiration during general anaesthesia:
Adult: 150 mg given 2 hr before induction of anaesth, and preferably a dose of 150 mg on the previous evening. In obstetric patients at the start of labour, 150 mg may be given, and repeated 6 hrly if required.
Adult: 300 mg daily at bedtime or 150 mg bid in combination with amoxicillin 750 mg and metronidazole 500 mg tid given for 2 wk. Treatment with ranitidine must be continued for a further 2 wk.
Benign gastric and duodenal ulceration:
Adult: Initially, 300 mg daily at bedtime or 150 mg bid for 4-8 wk; 300 mg bid for 4 wk may be used in duodenal ulcer to improved healing. Maintenance: 150 mg daily at bedtime. Max: 300 mg bid.
Child: 1 mth to 16 yr 4-8 mg/kg daily in 2 divided doses. Max: 300 mg/day. Treatment duration: 4-8 wk. Maintenance: 2-4 mg/kg once daily. Max: 150 mg/day.
Manufacturer: Square Pharmaceutical Ltd.