Nitazox Oral Suspension contains the active ingredient Nitazoxanide, a synthetic antiprotozoal agent. Nitazoxanide is well absorbed from GIT. It interferes with Pyruvate Ferredoxin Oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is important for anaerobic glucose energy metabolism. This results in cell swelling, membrane damage resulting in dysfunction of the parasite. When Nitazoxanide is administered with food, the AUC in plasma is increased almost two-fold and the Cmax is increased by almost 50%.
Nitazox Tablet 500 mg
Age 1-3 years: 5 ml of Nitazoxanide Suspension (100 mg Nitazoxanide) every 12 hours for 3 days.
Age 4-11 years: 10 ml of Nitazoxanide Suspension (200 mg Nitazoxanide) every 12 hours for 3 days.
Age ≥ 12 years: Nitazoxanide Tablet or 25 ml of Nitazoxanide Suspension (500 mg Nitazoxanide) every 12 hours for 3 days.
Nitazoxanide should be taken with food.