Osmosol IV Infusion
৳ 155.00
The adult dose of Mannitol ranges from 50 to 100 gm by IV infusion. The rate of administration is usually adjusted to maintain a urine flow of at least 30 to 50 ml/hr. Total dosage, concentration and the rate of administration depends on fluid requirement, urinary output and the severity of the condition being treated
Renal insufficiency-
Adults: 50 to 100 g of Mannitol administered at a rate adjusted to maintain a urine flow of at least 30 to 50 ml/hr.
Children: 2 gm/kg or 60 gm/m2 of body surface area administered over a period of 2 to 6 hrs.
Cerebral edema, elevated intracranial pressure, elevated intraocular pressure, Glaucoma-
Adults: 1.5 to 2 gm/kg administered over a period of 30 to 60 minutes.
Children: 1 to 2 gm/kg body wt. or 30 to 60 gm/m2 of body surface area administered over a period of 30 to 60 mins.
Adjunctive therapy for removal of toxic substances-
Adults: 50 to 200 g of Mannitol administered at a rate adjust to maintain a urine flow of at least 100 to 500 ml/hr.
Children: 2 gm/kg or 60 gm/m2 of body surface area
For termination of pregnancy 50 gm of Mannitol (250 ml of Mannitol) is instilled into the amniotic cavity which induces abortion in a high proportion of pregnancies.
Osmosol® 20 is a clear, almost colorless and sterile solution of Mannitol. Each 100ml of Osmosol® 20 contains Mannitol BP 20g. Administered parenterally, Osmosol® 20 raises the osmotic pressure of the plasma, thus drawing water out of body tissues and produces an osmotic diuresis. Osmosol® 20 is principally used by IV infusion as an osmotic diuretic to preserve renal function in acute renal failure and to reduce raised intracranial and intraocular pressure. Osmosol® 20 is also used as an irrigating solution to prevent hemolysis and hemoglobin buildup during transurethral prostatic resection. It is useful in the management of acute drug poisoning where a route of elimination is through kidney. Besides these, it is also used in symptomatic relief of edema, reperfusion injury, termination of pregnancy, and bowel preparation.
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