Tapentadol is a centrally-acting synthetic analgesic which inhibits ascending pain pathways by binding to ?-opiate receptor in the CNS and inhibiting norepinephrine reuptake, thus altering pain perception and response.
(in Tablet form)
Moderate to severe acute pain: As immediate-release preparation: Initially, 50 mg, 75 mg or 100 mg 4-6 hrly, depending on pain intensity. On day 1, a 2nd dose may be given 1 hr after the initial dose if pain relief is inadequate; subsequent dose may be given 4-6 hrly, adjust according to response. Max: 700 mg on day 1, 600 mg daily on subsequent days.
Chronic pain, Neuropathic pain: Moderate to severe chronic pain; Neuropathic pain associated with diabetic peripheral neuropathy: As modified-release preparation: Initially, 50 mg 12 hrly, may increase by 100 mg every 3 days if pain relief is inadequate. Max: 500 mg daily.
Manufacturer: Square Pharmaceutical Ltd.
Out of stock