Penvik Powder for Suspension
৳ 18.34
The dosge of Phenoxymethyl Penicillin should be determded accoedgto the snsitivityof the raustive mnro-orgnism and tie severity of tie infection, and adjusted to the clinical respons of the patient
Adults: 250-500 mg 6 hourly
Children: 125-250 mg 6 hourly
125 mg/5 ml Syrup: 1 to 2 teaspoonful (5-10 ml) 6 homiy
250 mg/5 ml Syrup: ? to 1 teaspoonful (2.5-5 ml) 6 hourly
Infants: 62.5 -125 mg 6 hourly
125 mg/5 ml Syrup: ? to 1 tea spoonful (2.5-5 ml) 6 hourly, or as prescribed by the physician.
Phenoxymethyl Penicillin is best taken with a empty stomach, preferably at least 1 hour before or 2 hour after meal.
Phenoxymethyl Penicillin inhibits the final cross-linking stage of peptidoglycan production through binding and inactivation of transpeptidases on the inner surface of the bacterial cell membrane, thus inhibiting bacterial cell wall synthesis.
By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Phenoxymethyl Penicillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Phenoxymethyl Penicillin interferes with an autolysin inhibitor.
It may be less active against some susceptible organisms, particularly gm-ve bacteria. It is suitable for mild to moderate infections.
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