In humans, natural supply of vitamin D depends mainly on exposure to the ultraviolet rays of the sun for conversion of 7-dehydrocholesterol to vitamin D3 (cholecalciferol) in the skin. Calcipotriol is a synthetic analog of vitamin D3. Calcipotriol regulates skin cell production and development, thereby modifying the abnormal growth and production of keratinocytes, responsible for the plaque psoriasis.
Planex Ointment 10 gm
Adults: Calcipotriol cream, ointment or Scalp solution should be applied topically to the affected area twice daily (i.e. in the morning and in the evening). Less frequent application may be indicated after the initial period of treatment. After satisfactory improvement has occurred, treatment should be discontinued. If recurrence takes place after discontinuation, the treatment may be reinstituted. Experience is lacking in the use of calcipotriol for periods longer than 1 year. The maximum recommended weekly dose of calcipotriol cream is 100gm/week.
Children: Calcipotriol cream, ointment or Scalp solution should not be used in children, as there is inadequate experience with its use.