Protolan® is a proton pump inhibitor. It is an irreversible inhibitor of the parietal cell H+-K+ATPase, which leads to profound inhibition of gastric acid secretion. It is indicated in Duodenal ulcer,Gastric ulcer, Esophagitis/Ulceration, Zollinger-Ellison syndrome, Resistant ulcers and esophagitis, Eradication of Helicobacter pylori in the treatment of peptic ulcer ( in combination with antibiotics)
Protolan 30mg Capsule
Benign gastric ulcer: 30 mg daily in the morning for 8 weeks.
Duodenal ulcer: 30 mg daily in the morning for 4 weeks; maintenance 15 mg.
NSAID-associated duodenal or gastric ulcer: 15-30 mg daily for 4 weeks, followed by a further 4 weeks if not fully healed.
Zollinger-Ellison syndrome (and other hypersecretory conditions): Initially 60 mg once daily adjusted according to response; daily doses of 120 mg or more is given in two divided doses.
Gastroesophageal reflux disease: 30 mg daily in the morning for 4 weeks, followed by a further 4 weeks if not fully healed; maintenance 15-30 mg daily.
Acid-related dyspepsia: 15-30 mg daily in the morning for 2-4 weeks.