Sulfinpyrazone increases urinary excretion of uric acid by competitively inhibiting tubular reabsorption of uric acid, thus lowering serum urate concentration and eventually reducing urate deposits in the tissues.
Pyrazone 200 Tablet
200-400 mg daily in two divided doses, with meals or milk, gradually increasing when necessary to full maintenance dosage in one week.
Maintenance: 400 mg daily, given in two divided doses, as above. This dosage may be increased to 800 mg daily, if necessary and may sometimes be reduced to as low as 200 mg daily after the blood urate level has been controlled.