Retabac Ointment
Retapamulin
(in Ointment form)
Dosage:
Adult: As 1% ointment: Apply onto affected area bid for 5 days. Re-evaluate if there is no response after 3 days of treatment. Total treatment area: ?100 cm2 total body surface area.
Child: As 1% ointment: ?9 mth: Apply onto affected area bid for 5 days. Total treatment area: ?2% of total body surface area.
Manufacturer: Square Pharmaceutical Ltd.
Retapamulin is a pleuromutilin antibacterial isolated from the fungus Clitopilus passeckerianus. It is a bacteriostatic agent that works by inhibiting biosynthesis of bacterial protein by binding at protein L3 on the ribosomal 50S subunit. It also inhibits peptidyl transfer and blocks P-site interactions at this site, thus preventing the formation of active 50S ribosomal subunits.
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