Secnidazole is active against E histolytica, G lamblia, T vaginalis, Clostridium spp, B fragilis, Gardnerella spp. The drug enters the microorganisms by diffusion and is reduced intracellularly by low oxidation-reduction potential ferredoxin which then result in DNA damage.
Secnid DS Tablet
(in Suspension form)
Severe invasive amoebiasis
Adult: 1.5 g daily as single or in divided doses for 5 days.
Child: 30 mg/kg daily for 5 days.
Trichomoniasis, Amoebiasis, Giardiasis
Adult: 2 g as a single dose.
Child: 30 mg/kg as a single dose.
Manufacturer: Square Pharmaceutical Ltd.