Cefixime binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
T-Cef Powder for Suspension 30 ml
The usual course of treatment is 7 days. This may be continued for up to 14 days if required. The daily dose can be given in 1–2 divided doses.
Adult and child over 10 years: 200–400 mg daily
Child over 6 months: 8 mg/kg daily
6 months to 1 year: 75 mg (3.75 ml) daily,
1 to 4 years: 100 mg (5 ml) daily
5 to 10 years: 200 mg (10 ml) daily
Typhoid and paratyphoid :
Adult: 200 mg 12 hourly
Child: 10 mg/kg 12 hourly
Adult: 400-800 mg as a single dose