Ceftazidime binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Tazid IM/IV Injection
(in Injection form)
Prophylaxis of surgical infection in patients undergoing prostate surgery:
Adult: 1 g at induction of anaesth repeated if necessary upon removal of catheter. It is given as deep IM inj, slow IV inj over 3-5 min or IV infusion for up to 30 min.
Elderly: >80 yr Max: 3 g daily.
Pseudomonal lung infections in cystic fibrosis:
Adult: 100-150 mg/kg 8 hrly as deep IM inj, slow IV inj over 3-5 min or IV infusion for up to 30 min. Max: 9 g daily.
Child: <40 kg: 150 mg/kg daily in 3 divided doses. Max: 6 g daily. Elderly: >80 yr Max: 3 g daily
Manufacturer: Square Pharmaceutical Ltd.