Tyclav® (375 mg Tab, 625 mg Tab, 1 g Tab, 100 ml Susp, 50 ml bid, 0.6 gm Inj and 1.2 gm Inj) is an antibacterial combination consisting of amoxicillin and the beta-lactamase inhibitor, clavulanate potassium.
Tyclav Tablet 250 mg+125 mg
Dose of Tablets:
Adults and children over 12 years:
The usual adult dose is one Tyclav® 625 Tablet every 12 hours or one Tyclav® 375 Tablet every 8 hours. For more severe infections and infections of the respiratory tract, the dose should be one Tyclav® 1 g Tablet every 12 hours or one Tyclav® 625 Tablet every 8 hours.
Dose of Powder for Suspensions:
Tyclav® Powder for Suspension:
Neonate: 0.25 ml/kg 3 times daily.
1 month–1 year: 0.25 ml/kg 3 times daily, dose doubled in severe infection.
1–6 years: 5 ml 3 times daily or 0.25 ml/kg 3 times daily, dose doubled in severe infection.
6-12 years: 10 ml 3 times daily, dose doubled in severe infection.
Tyclav® bid Powder for Suspension:
2 month-2 years: 0.15 ml/kg twice daily, doubled in severe infection.
2-6 years (13-21 kg): 2.5 ml twice daily, doubled in severe infection.
7-12 years (22-40 kg): 5 ml twice daily, doubled in severe infection.
12-18 years (over 40 kg): 10 ml twice daily, three times daily in severe infection.
Dose of Injections:
Usually 1.2 g every 8 hours, increased in more severe infections to 1.2 g every 6 hours.
Adult dosage for surgical prophylaxis
The usual dose is 1.2 g at induction, for high risk procedures (e.g., colorectal surgery) up to 2-3 further doses of 1.2 g may be given every 8 hours.
0 to 3 months: 30 mg/kg every 8 hours (every 12 hours in the perinatal period and in premature infants).
3 months to 12 years: Usually 30 mg/kg every 8 hours increased in more serious infections to 30 mg/kg every 6 hours.